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Preparation process and physicochemical properties of PS-DOX and ApoE-PS-DOX. (A) Illustration of preparation process of ApoE-PS-DOX. (B) Size distribution measured using DLS. Inset: Transmission electron microscopy (TEM) image of ApoE20-PS-DOX (bar: 100 nm). (C) Stability of ApoE20-PS-DOX under different conditions. (D) Responsiveness of ApoE20-PS-DOX under 10 mM GSH. (E) GSH-triggered drug release from ApoE20-PS-DOX in PB and PB + 10 mM GSH at 37 °C.
