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. 2021 Jun 15;16:4073–4085. doi: 10.2147/IJN.S308057

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© 2021 Gao et al.

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(A) Representative images of immunohistochemical analysis of each group for the evaluation of Ki-67 and CD31 (×400). (B) The quantitative analysis of Ki-67 expression in each group. (C) The quantitative analysis of vascularization in each group.

Notes: Data are presented as mean ± standard deviation (n = 3; ** P < 0.01 of indicated groups vs NS group; # P < 0.05, ## P < 0.01 of indicated NCTD-NPs/Dox Gel vs Free NCTD/Dox).

Abbreviations: NS, normal saline; NCTD, norcantharidin; Dox, doxorubicin; NPs, nanoparticles.