Table 5:
Univariate analysis of poor prognosis in children with epilepsy [n(%), x̄±sd]
| Factors | n | Effective group (n=71) | Ineffective group (n=12) | χ2/t | P |
|---|---|---|---|---|---|
| Gender | 0.001 | 0.971 | |||
| Male | 55 | 45(81.82) | 10(18.18) | ||
| Female | 28 | 23(82.14) | 5(17.86) | ||
| Age (yr) | 0.013 | 0.989 | |||
| 83 | 8.72±7.33 | 8.69±7.44 | |||
| Course of disease (year) | 1.061 | 0.318 | |||
| 83 | 1.2±0.3 | 1.3±0.4 | |||
| Weight (kg) | 0.055 | 0.956 | |||
| 83 | 15.32±8.12 | 15.18±8.08 | |||
| Family history of epilepsy | 0.003 | 0.957 | |||
| With | 34 | 29(85.29) | 5(14.71) | ||
| Without | 49 | 42(85.71) | 7(14.29) | ||
| Production mode | 0.111 | 0.738 | |||
| Eutocia | 52 | 45(86.54) | 7(13.46) | ||
| Caesarean | 31 | 26(83.87) | 5(16.13) | ||
| Seizure type | 6.200 | 0.013 | |||
| Focal seizure | 48 | 45(93.75) | 3(6.25) | ||
| A generalized attack | 35 | 26(74.29) | 9(25.71) | ||
| Parental smoking history | 0.002 | 0.964 | |||
| With | 41 | 35(85.37) | 6(14.63) | ||
| Without | 42 | 36(85.71) | 6(14.29) | ||
| Parental drinking history | 0.449 | 0.503 | |||
| With | 48 | 40(83.33) | 8(16.67) | ||
| Without | 35 | 31(88.57) | 4(11.43) | ||
| Place of residence | 0.105 | 0.746 | |||
| Countryside | 59 | 50(84.75) | 9(15.25) | ||
| City | 24 | 21(87.50) | 3(12.50) | ||
| NGF (pg/ml) | 5.166 | <0.001 | |||
| 83 | 400.16±86.56 | 540.81±91.37 | |||
| GABA (pg/ml) | 2.442 | 0.016 | |||
| 83 | 462.37±83.23 | 400.44±67.31 | |||
| NSE (ug/L) | 12.60 | <0.001 | |||
| 83 | 13.53±3.68 | 28.62±4.72 | |||
| Treatment methods | 6.938 | <0.001 | |||
| Sodium valproate therapy | 40 | 30(75.00) | 10(25.00) | ||
| Treatment of Sodium Valproate Combined with Levetiracetam | 43 | 41(95.35) | 2(4.65) |