Table 1.

Mutations in African camel S proteins compared to EMC/2012

Residue no.	Domain within S	EMC	BF	Ethi-118S	Ethi-126S	Mor	Nga
26	S1-NTD	V	A	A	A	A	A
89	S1-NTD	A	S	.	.	S	.
139	S1-NTD	T	.	I	I	.	.
158	S1-NTD	D	.	Y	Y	.	.
167	S1-NTD	H	.	.	.	.	Y
194	S1-NTD	H	Y	Y	Y	.	Y
390	S1-RBD	S	.	F	F	.	.
424	S1-RBD	T	I	.	.	I	.
431	S1-RBD	A	.	.	.	.	.
457	S1-RBD	S	.	.	.	.	.
495	S1-RBD	L	.	.	.	.	F
515	S1-RBD	P	.	.	L	.	.
588	S1-RBD	L	.	.	.	.	F
597	S1-RBD	A	.	V	V	.	.
626	S1-SD1	R	.	P	P	.	.
677	S1-SD2	V	.	.	.	.	.
773	S2-L	L	.	.	.	.	.
810	S2-L	V	.	.	.	.	.
851	S2-UH	A	.	E	E	.	.
856	S2-L	S	Y	.	.	Y	Y
884	S2-L	R	.	.	.	L	.
1020	S2-HR1	Q	.	.	.	.	.
1158	S2-CH	A	S	S	S	S	L
1193	S2-SD3	A	.	.	.	.	.
1200	S2-SD3	L	.	.	.	.	F
1209	S2	V	.	.	.	L	.
1302	S2-TM	G	.	S	S	.	.

. Represents no changes in amino acid compared to EMC/2012 strain. Amino acids are identified using single-letter codes. CH, central helix; HR, heptad repeat; L, linker region; NTD, N-terminal domain; SD, subdomain; TM, transmembrane region/domain; UH, upstream helix (45).