Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 9;118(24):e1922586118. doi: 10.1073/pnas.1922586118

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published under the PNAS license.

PMC Copyright notice

Fig. 6. — Knockdown of Scratch2 in rat vPAG results in depression-like behaviors. (A and B) The mRNA level of Scratch2 (A) or GalR1 (B) was determined by real-time PCR in the vPAG after the injection of Lenti-Scratch2-siRNA virus. Data are presented as mean ± SD (n = 3 per group). In A, T₁₄ = 3.171, P < 0.05. In B, T₁₄ = 2.807, P < 0.05. (C) Decreased sucrose intake in the sucrose preference test was observed after injection of Lenti-Scratch2-siRNA virus. One-way ANOVA, F(2, 21) = 10.01, P < 0.001. (D) Increased immobility time in the FST was induced after injection of Lenti-Scratch2-siRNA virus. One-way ANOVA, F(2, 21) = 6.387, P < 0.01. (E and F) Decreased central area time (E) and total distance (F) in the OFT was observed after injection of Lenti-Scratch2-siRNA virus. In E, One-way ANOVA, F(2, 21) = 9.776, P < 0.001. In F, One-way ANOVA, F(2, 21) = 12.81, P < 0.001. Data are presented as mean ± SE (n = 8 per group). *P < 0.05, **P < 0.01.