Table 1. Baseline characteristics and predictors of AKI in patients after TAVR.
AKI, acute kidney injury; IQR, interquartile range; TAVR, transcatheter aortic valve replacement
| Variable | No AKI (153,715) | With AKI (20,045) | No AKI vs. AKI (multivariate analysis), OR (95% CI) |
| Age, median (IQR) | 82 (75-86) | 82 (74-87) | 1.00 (0.97-1.04) (reference age < 75 years) |
| Male gender | 81590 (53.1%) | 11585 (57.8%) | 1.12 (1.08-1.16) (reference to female) |
| Caucasian | 128800 (87.4%) | 15875 (83.4%) | Reference |
| African Americans | 6060 (4.1%) | 1005 (5.3%) | 0.74 (0.67-0.81) |
| Hispanics | 6855 (4.6%) | 1285 (6.7%) | 0.71 (0.63-0.80) |
| Chronic kidney disease | 33645 (21.9%) | 10575 (52.8%) | 3.52 (3.40-3.64) |
| Weight loss | 3870 (2.5%) | 1865 (9.3%) | 3.01 (2.82-3.20) |
| Liver disease | 4060 (2.6%) | 1405 (7.0%) | 2.29 (2.13-2.46) |
| Congestive heart failure | 110385 (71.8%) | 17205 (85.8%) | 2.01 (1.92-2.10) |
| Coagulopathy | 17270 (11.2%) | 4315 (21.5%) | 1.82 (1.75-1.90) |
| Cerebrovascular disease | 17320 (11.3%) | 2930 (14.6%) | 1.30 (1.24-1.36) |
| Solid organ tumor | 3655 (2.4%) | 605 (3.0%) | 1.23 (1.11-1.36) |
| Chronic obstructive pulmonary disease | 46145 (30.0%) | 7095 (35.4%) | 1.21 (1.17-1.25) |
| Metastatic cancer | 995 (0.6%) | 150 (0.7%) | 1.16 (0.95-1.41) |
| Peripheral vascular disease | 33015 (21.5%) | 5130 (25.6%) | 1.15 (1.11-1.19) |
| Obesity | 25870 (16.8%) | 3335 (16.6%) | 1.01 (0.97-1.05) |
| Lymphoma | 1060 (0.7%) | 125 (0.6%) | 0.99 (0.81-1.20) |
| Alcohol use | 240 (0.2%) | 45 (0.2%) | 0.98 (0.70-1.39) |
| Hypothyroidism | 31350 (20.4%) | 4050 (20.2%) | 0.98 (0.94-1.02) |
| Coronary artery disease | 106475 (69.3%) | 13950 (69.6%) | 0.92 (0.89-1.00) |
| Hypertension | 136605 (88.9%) | 18015 (89.9%) | 0.90 (0.85-1.0) |
| Diabetes mellitus | 25140 (16.4%) | 1990 (9.9%) | 0.76 (0.72-0.80) |
| Income | |||
| 0-25th percentile | 32110 (21.2%) | 4485 (22.7%) | Reference |
| 25th-50th percentile | 38530 (25.4%) | 5210 (26.4%) | 1.08 (1.03-1.13) |
| 50th-75th percentile | 40805 (26.9%) | 4955 (25.1%) | 1.05 (1.00-1.10) |
| 75th-100th percentile | 39990 (26.4%) | 5075 (25.7%) | 0.93 (0.89-0.97) |
| Urban | 1380 (0.9%) | 110 (0.5%) | Reference |
| Urban non-teaching | 14550 (9.5%) | 1625 (8.1%) | 0.56 (0.46-0.69) |
| Urban teaching | 137785 (89.6%) | 18310 (91.3%) | 0.85 (0.80-0.90) |