Table 1.

Clinical data for prioritization in neuro-oncology point-of-care capture

Category	CDASH domain	Class	Factor
Diagnosis	Findings	Pathology	Histology
			Molecular features
			Molecular testing platform
			WHO grade
			Location
		Imaging	Modality
			Finding
		Biomarker	Test
			Finding
		Staging	Cancer stage
Intervention	Exposure	Surgery	Extent
			Location
		Radiation	Modality
			Dose
		Disease-modifying therapy	Agent
			Start date
			Completion date
			Cycles completed
			Adverse event
			Modification*
			Outcome
Surveillance	Findings	Imaging	Modality
			Outcome
		Exam	Functional status score
			Clinical exam findings
			Neurocognitive testing
		Patient-reported outcomes	Test
			Score
Outcome modifiers	Events	Associated comorbidities/risks	Seizure
			DVT/PE
			Other cancers/tumors
		Comorbidities	From EHR
		Medications	Steroids
			Others
	Special purpose	Social factors	Support

Variables in italics are least likely to have an existing structured data field in the EHR and are therefore most critical for clinician reporting. All reported factors require a minimum of an associated date and unit of measure

CDASH Clinical Data Acquisition Standards Harmonization, EHR Electronic health record, DVT Deep vein thrombosis, PE Pulmonary embolism, WHO World Health Organization

^*“Modification” is a CDASH “special purpose” domain