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. Author manuscript; available in PMC: 2021 Jun 20.
Published in final edited form as: Brain Stimul. 2020 Jul 10;13(5):1333–1348. doi: 10.1016/j.brs.2020.07.002

Table 3.

Brain areas with significantly(p < 0.005) greater deactivation in participants receiving sham compared to non-invasive cervical vagal nerve stimulation (nVNS) while listening to personalized traumatic scripts as measured with positron emission tomography. Significant clusters are presented by size (number of voxels) and location (Brodmann area, cluster peak Talairach coordinates). Sub-cluster peaks are also identified.

Voxel Number Brain Region Brodmann Area Talairach
Z Score
X Y Z

136 R Posterior Cingulate 29 16 −48 11 4.64
R Occipital Lobe, Precuneus 26 −51 21 2.68
23 R Temporal Lobe, Middle Gyrus 21 63 3 −9 4.49
129 R Temporal Lobe, Transverse Gyrus 42 61 −13 16 4.26
R Parietal Lobe, Postcentral Gyrus 43 67 −7 15 4.12
R Temporal Lobe, Superior Gyrus 22 69 −3 9 3.44
99 L Occipital Lobe, Lingual Gyrus 17 −20 −80 2 3.90
L Occipital Lobe, Cuneus 17 −16 −89 6 3.76
L Occipital Lobe, Cuneus 17 −12 −79 7 3.40
212 R Occipital Lobe, Inferior Gyrus 19 38 −68 −2 3.69
R Occipital Lobe, Inferior Gyrus 19 44 −74 −5 3.58
R Occipital Lobe, Middle Gyrus 37 40 −64 6 3.42
41 R Anterior Cingulate 10 16 47 −1 3.62
51 L Occipital Lobe, Middle Gyrus 19 −34 −83 14 3.56
L Occipital Lobe, Middle Gyrus −32 −71 15 3.36
38 L Frontal Lobe, Medial Gyrus 10 −20 49 13 3.55
44 L Posterior Cingulate Gyrus 31 −14 −27 42 3.54
L Posterior Cingulate Gyrus 31 −8 −23 45 2.98
27 L Frontal Lobe, Precentral Gyrus 6 −32 2 35 3.39
46 L Temporal Lobe, Middle Gyrus −44 −46 9 3.36
L Temporal Lobe, Superior Gyrus 22 −40 −52 13 3.26
L Temporal Lobe, Superior Gyrus 22 −55 −44 11 3.22
12 R Frontal Lobe, Paracentral Lobule 5 4 −32 54 3.35
81 R Occipital Lobe, Middle Gyrus 18 26 −85 2 3.35
R Occipital Lobe, Cuneus 30 22 −70 8 3.14
12 L Frontal Lobe, Paracentral Lobule 5 −4 −40 57 3.31
26 L Frontal Lobe, Precentral Gyrus 6 −44 −14 26 3.31
28 L Frontal Lobe, Middle Frontal Gyrus 46 −40 14 18 3.29
15 R Anterior Cingulate 24 10 35 3 3.28
14 R Cerebellum 30 −36 −22 3.27
19 L Frontal Lobe, Medial Gyrus 9 −2 51 14 3.26
45 R Frontal Lobe, Precentral Gyrus 9 42 4 32 3.25
16 R Posterior Cingulate 30 8 −69 13 3.22
17 L Frontal Lobe, Precentral Gyrus 6 −53 −6 30 3.21
45 R Occipital Lobe, Cuneus 18 24 −77 17 3.21
R Parietal Lobe, Precuneus 31 18 −73 22 3.14
16 R Anterior Cingulate 32 12 25 36 3.21
13 L Parietal Lobe, Inferior Lobule 40 −46 −37 29 3.16
24 L Occipital Lobe, Precuneus 31 −20 −63 25 3.16
L Temporal Lobe, Middle Gyrus 39 −28 −63 27 2.78
12 L Parietal Lobe, Precuneus 7 −14 −58 36 3.14
11 L Posterior Cingulate 30 −26 −64 11 3.03
20 R Temporal Lobe, Middle Gyrus 21 59 10 −27 3.00
R Temporal Lobe, Superior Gyrus 38 59 11 −19 2.71
11 L Occipital Lobe, Cuneus 18 −20 −79 17 2.98
12 R Frontal Lobe, Superior Frontal Gyrus 9 6 48 33 2.90