1.
AS患者一般资料及随访期病情特点
Clinical and demographic characteristics of AS patients in the study
| Variables | Baseline | 13 weeks | 26 weeks | 39 weeks | 52 weeks |
| *P < 0.05 vs baseline data at each follow-up time point; ASDAS-CRP: CRP-based disease activity score; LBP: Low back pain score; BASDAI: Bath ankylosing spondylitis disease activity index; BASFI: Bath ankylosing spondylitis functional index; BASMI: Bath ankylosing spondylitis metrology index. | |||||
| Age (year) | 30.91±8.64 | - | - | - | - |
| Male/Female | 50/7 | - | - | - | - |
| BMI (kg/m2) | 22.52±2.96 | - | - | - | - |
| Disease duration (years) | 7.04±6.66 | - | - | - | - |
| HLA-B27 (+/-) | 48/9 | - | - | - | - |
| ESR (mm/h) | 6.4±5.03 | 7.32±5.67* | 7.34±4.19* | 8.81±8.29 | 10.57±7.44* |
| CRP (mg/L) | 2.61±3.37 | 3.14±3.97 | 3.64±4.69 | 3.91±6.55 | 7.43±14.88* |
| ASDAS-CRP | 1.19±0.64 | 1.42±0.79* | 1.36±0.76* | 1.56±0.90* | 1.75±1.18* |
| LBP | 1.90±1.51 | 2.48±2.01* | 2.21±1.76* | 2.59±2.14* | 2.96±2.33* |
| BASDAI | 1.65±0.96 | 2.15±1.41* | 1.94±1.24* | 2.36±1.68* | 2.82±2.07* |
| BASFI | 10.69±9.13 | 12.83±13.04* | 11.57±11.51 | 14.66±14.04* | 14.42±14.71* |
| BASMI | 2.51±1.30 | 2.65±1.44 | 2.43±1.26 | 2.59±1.08 | 3.51±1.32* |