Table 6.
Associations of myelin density with puberty stage and gender.
| Age | Gender | |||||||
|---|---|---|---|---|---|---|---|---|
| Region | rpds | (95% CI) | βpds | (95% CI) | P | βmale | (95% CI) | P |
| GM frontal | 0.20 | (0.05, 0.34) | 3.4 | (0.7, 6.1) | 0.015 | 11.5 | (4.7, 18.3) | 0.001* |
| GM occipital | 0.19 | (0.02, 0.37) | 3.0 | (0.5, 5.6) | 0.019 | 10.4 | (4.1, 16.7) | 0.001* |
| GM parietal | 0.29 | (0.16, 0.42) | 4.4 | (2.0, 6.7) | <0.001* | 8.8 | (2.9, 14.6) | 0.004* |
| GM temporal | 0.15 | (0.00, 0.30) | 2.5 | (−0.3, 5.3) | 0.075 | 8.4 | (1. 4, 15.3) | 0.018 |
| GM insula | −0.03 | (−0.18, 0.13) | −0.7 | (−5.1, 3.7) | 0.76 | 9.2 | (−1.8, 20.1) | 0.10 |
| Subcortical | 0.11 | (−0.05, 0.27) | 1.5 | (−0.7, 3.7) | 0.17 | 8.7 | (3.3, 14.1) | 0.002* |
| WM frontal | 0 12 | (−0.03, 0 27) | 09 | (−0.3, 2.0) | 014 | 3.7 | (0.8, 6.6) | 0.011 |
| WM occipital | 0.09 | (−0.07, 0.25) | 0.7 | (−0.6, 1.9) | 0.28 | 3.9 | (1.0, 6.9) | 0.010 |
| WM parietal | 0.10 | (−0.04, 0.24) | 0.7 | (−0.4, 1.8) | 0.22 | 2.6 | (−0.1, 5.3) | 0.064 |
| WM temporal | 0.21 | (0.07, 0.34) | 1.5 | (0.3, 2.6) | 0.013 | 2.9 | (0.1, 5.8) | 0.043 |
| WM insula | −0.04 | (−0.20, 0.11) | −0.3 | (−1.8, 1.1) | 0.64 | 1.8 | (−1.8, 5.4) | 0.31 |
rpds = partial Pearson’s correlation coefficient between mean myelin density and age, adjusted for gender.
βpds = difference in mean MPF (% of the mean) per 1-level increase in PDS.
βmale = difference in mean MPF (% of the mean) between genders (males - females).
*
Statistically significant after Bonferroni correction.