Table 4:
Genetic model | Subgroup | N | OR | P value | I2% | OR adjusted* | P-value adjusted* | I2% adjusted* |
---|---|---|---|---|---|---|---|---|
GT+TT vs GG | Overall IIP | 13 | 4.34 [3.22, 5.84] | <0.0001 | 69% | 5.13[4.41,5.97] | <0.0001 | 37% |
Asian | 4 | 2.09 [1.44, 3.05] | <0.0001 | 46% | 4.13[2.15,7.95] | <0.0001 | 0% | |
Caucasian | 9 | 4.95 [3.85, 6.35] | <0.0001 | 52% | 4.95 [3.85, 6.35] | <0.0001 | 52% | |
IPF | 10 | 4.39 [3.17, 6.10] | <0.0001 | 75% | 5.22[4.46, 8.10] | <0.0001 | 42% | |
T vs G | Overall IIP | 22 | 4.03 [3.34–4.86] | <0.0001 | 79% | 4.38[3.82,5.03] | <0.0001 | 34% |
Asian | 4 | 2.64 [1.60–4.34] | <0.0001 | 27% | 4.05[2.11, 7.78] | <0.0001 | 0.40 | |
Caucasian | 18 | 4.22 [3.47–5.14] | <0.0001 | 81% | 4.43[4.07, 4.83] | <0.0001 | 33.89 | |
IPF | 18 | 4.06 [3.31–4.97] | <0.0001 | 83% | 4.47[4.10, 4.87] | <0.0001 | 30.71 |
Note:
adjusted by removing the data of Jiang H et al. and Noth I et al