Table 6.
Clinical chemistry results of female (F) rats. Group mean values and standard deviation (SD).
| Clinical chemistry | Units | Groups of female rats (dose level in mg TOS/kg bw/day) |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| 1F (0) |
2F (110.3) |
3F (363.8) |
4F (1102.5) |
||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||
| ALP | U/L | 39 | (7.9) | 36 | (9.5) | 44 | (10.4) | 37 | (8.0) |
| ALT | U/L | 46 | (8.4) | 45 | (10.6) | 43 | (5.8) | 47 | (7.6) |
| AST | U/L | 84 | (30.5) | 73 | (12.6) | 78 | (16.1) | 84 | (18.2) |
| Bi Ac | μmol/L | 53.7 | (29.10) | 33.8 | (13.49) | 37.4 | (24.95) | 33.0∗ | (16.21) |
| Urea | mmol/L | 6.79 | (0.729) | 6.86 | (0.665) | 6.36 | (0.865) | 6.72 | (1.406) |
| BUN | mmol/L | 6.79 | (0.729) | 6.86 | (0.665) | 6.36 | (0.865) | 6.72 | (1.406) |
| Creat | μmol/L | 30 | (3.2) | 31 | (2.5) | 30 | (4.3) | 30 | (3.2) |
| Gluc | mmol/L | 6.68 | (0.777) | 7.44 | (0.855) | 7.66∗ | (0.591) | 7.89∗ | (1.534) |
| Chol | mmol/L | 2.04 | (0.397) | 2.30 | (0.569) | 2.26 | (0.385) | 2.06 | (0.256) |
| HDL | mmol/L | 1.69 | (0.313) | 1.87 | (0.402) | 1.90 | (0.307) | 1.72 | (0.212) |
| LDL | mmol/L | 0.12 | (0.031) | 0.16 | (0.067) | 0.16 | (0.057) | 0.12 | (0.035) |
| Na | mmol/L | 141 | (1.1) | 142 | (1.4) | 142∗ | (1.3) | 142∗ | (1.6) |
| K | mmol/L | 3.85 | (0.107) | 3.95 | (0.318) | 3.92 | (0.165) | 3.74 | (0.213) |
| Total Prot | g/L | 72 | (3.5) | 73 | (1.8) | 74 | (2.4) | 75∗ | (3.0) |
| Alb | g/L | 43 | (1.8) | 44 | (1.6) | 44 | (1.5) | 44 | (1.8) |
| A/G | Ratio | 1.46 | (0.099) | 1.47 | (0.113) | 1.47 | (0.074) | 1.41 | (0.063) |
Significantly different from the controls: ∗: P < 0.05; ∗∗: P < 0.01.
ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; Bi Ac: Bile acids – total; BUN: Blood urea nitrogen; Crea: Creatinine; Gluc: Glucose; Chol: Total cholesterol; HDL: High density lipoprotein; LDL: High density lipoprotein; Na: Sodium; K: Potassium; Total Prot: Total protein; Alb: Albumin and A/G: Albumin/globulin ratio.