Table 5.

Associations of pre-ICI corticosteroid use with pericardial disease and all-cause mortality

	N	Pericardial disease		All-cause mortality
		Number	HR	Number	HR
Entire cohort	126	42		65
Corticosteroid prior to initiation of ICI	12	7	2.11 (0.94 to 4.76), p=0.07	7	0.96 (0.44 to 2.12), p=0.93
Higher dose (>0.7 mg/kg prednisone)	7	5	2.56 (1.00 to 6.57), p=0.049	3	0.62 (0.19 to 1.98), p=0.42
Lower dose (<0.7 mg/kg prednisone)	5	2	1.33 (0.32 to 5.49), p=0.70	4	1.62 (0.59 to 4.48), p=0.35

Associations of pre-ICI corticosteroid use with pericardial disease and all-cause mortality in 42 patients who developed pericardial disease after ICI treatment vs 84 age-type and cancer-type matched control patients who did not develop pericardial disease after ICI treatment (design 2).

ICI, immune checkpoint inhibitor.