TABLE 2.

The core targets of TW in the treatment of DN.

Number	Target gene	Degree	Betweenness Centrality
1	AKT1	38	0.07379271
2	TP53	38	0.06725352
3	VEGFA	37	0.03571233
4	PTGS2	36	0.04609104
5	TNF	36	0.03240009
6	MMP9	35	0.05231183
7	JUN	34	0.01403485
8	FN1	33	0.01425303
9	CXCL8	33	0.01402184
10	NOS3	31	0.04440636
11	PPARG	31	0.02808594
12	RELA	29	0.01695853
13	ESR1	29	0.0150523
14	STAT1	28	0.01927069
15	MMP1	25	0.01576515
16	CREB1	25	0.01447089