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. 2021 Jun 7;9:680491. doi: 10.3389/fcell.2021.680491

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Copyright © 2021 Zhai, Wu, Wang, Fan, Xie, Wu, He, Qian, Tan, Yao, He and Shen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pathological assays of the engrafted zebrafish for patient #55. (A) The confocal image and (B) the H & E image of the engrafted zebrafish (4 dpi). (C) The enlarged yolk sac showing the tumor xenograft (black arrow indicating engrafted tumor cells), which did not develop to the adenoid structure as that in the patients (F). (D) CA199 expression in tumor xenograft (blank arrow) and (G) CA199 expression in primary tumor tissue. (E) HAPLN1 expression in tumor xenograft (blank arrow) and (H) HAPLN1 expression in primary tumor tissue.