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Histological assessment of selected hound dog tissues following treatment with CKLP1. Representative tissue sections from trabecular meshwork/aqueous plexus (A), retina (B), kidney (C), and liver (D) of hound dogs treated once daily with CKLP1 for 12–13 days were devoid of any pathological findings, indicating appropriate tolerance of CKLP1. APL, aqueous plexus; SC, Schlemm's canal; Scale bar, 50 μm.
