Table 1:

Characteristics of adult Medicaid beneficiaries with new depressive episodes by treatment with oral antipsychotic medications

	Total Episodes N=1,594,180 (100%)	APM Initiators N=223,430 (14.0%)		Non APM Initiators N=1,370,750 (86.0%)		P(Chi-Square)
		N	%	N	%
DEMOGRAPHICa
Sex
Male	351,141	70,172	31.4	280,969	20.5	<.0001
Female	1,243,018	153,257	68.6	1,089,761	79.5
Age (mean, SD)	35.9 (12.5)	36.8	12.0	35.8	12.5
Age						<.0001
18-24	366,984	43,452	19.5	323,532	23.6
25-34	436,432	56,920	25.5	379,512	27.7
35-44	363,539	58,826	26.3	304,713	22.2
45-54	271,765	45,373	20.3	226,392	16.5
55-64	155,460	18,859	8.4	136,601	10.0
Race Ethnicity						<.0001
White, non-Hispanic	847,429	109,183	48.9	738,246	53.9
African American, non-Hispanic	364,213	62,815	28.1	301,398	22.0
Hispanic	229,011	29,452	13.2	199,559	14.6
other	153,527	21,980	9.8	131,547	9.6
Medicaid Eligibility						<.0001
Disability	602,389	114,774	51.4	487,615	35.6
Low income	644,988	67,520	30.2	577,468	42.1
Other	346,803	41,136	18.4	305,667	22.3
Managed care (not FFS)	608,939	73,106	32.7	535,833	39.1	<.0001
CLINICAL&UTILIZATIONb
Primary Depression dxc	1,151,853	182,702	81.8	969,151	70.7	<.0001
Major Depressive Disorderc	515,680	116,569	52.2	399,111	29.1	<.0001
Anxiety	129,006	20,845	9.3	108,161	7.9	<.0001
Substance use disorder	179,800	36,817	16.5	142,983	10.4	<.0001
Personality disorders	5,827	1,552	0.7	4,275	0.3	<.0001
Self-harm	2,282	496	0.2	1,786	0.1	<.0001
Diabetes	130,165	17,016	7.6	113,149	8.3	<.0001
Cardiovascular Disease	276,154	38,711	17.3	237,443	17.3	.9662
Cerebrovascular Disease	26,636	3,981	1.8	22,655	1.7	.0001
Psychotherapy	42,795	6,942	3.1	35,853	2.2	<.0001
MH ER visitd						<.0001
No visit	1,544,285	210,808	94.4	1,333,477	97.3
1 to 2 visits	46,140	11,657	5.2	34,483	2.5
3 or more visits	3,755	965	0.4	2,790	0.2
MH hospital admissionsd	15,888	5,087	2.3	10,801	0.8	<.0001
MH outpatient visitsd						<.0001
No visit	1,312,994	167,919	75.2	1,145,075	83.5
1 to 2 visits	164266	30543	13.7	133723	133723	9.8
3 or more visits	116920	24968	11.2	91952	91952	6.7

^aat index date;

^bduring 180 baseline period including index date;

^cwithin Index date and index date+30 days;

^dprimary diagnosis.

APM: antipsychotic medication; FFS: fee-for-service; MH: mental health; ER: emergency room