Table 1.
Antipsychotic Prescribing Trends in Office-Based Medical Visits of Antidepressant Treated Adult Non-Psychotic Depression, United States, 1999 to 2010
| Variable | SGA Rx Rates |
AOR for Time Trend (95% CI)a,b | ||
|---|---|---|---|---|
| 99-02 | 03-06 | 07-10 | ||
| n=2,506 | n=2,686 | n=2,575 | ||
| Overall | 6.1 | 8.4 | 11.2 | 2.78 (1.84 – 4.20) |
| Demographic Characteristics | ||||
| Sex | ||||
| Male | 6.3 | 8.2 | 12.5 | 3.21 (1.78 – 5.83) |
| Female | 6.0 | 8.6 | 10.6 | 2.60 (1.59 – 4.24) |
| Race/Ethnicity | ||||
| White, non-Hispanic | 5.4 | 8.0 | 11.1 | 3.22 (2.14 – 4.84) |
| Other | 15.3* | 13.4 | 12.3 | 1.12 (0.41 – 3.08) |
| Age (years) | ||||
| 18 – 44 | 5.9 | 7.3 | 10.1 | 3.06 (1.73 – 5.43) |
| 45 – 64 | 7.0 | 10.5 | 10.5 | 2.17 (1.31 – 3.57) |
| > 65 | 4.6 * | 6.4 * | 12.2 | 4.60 (1.34 – 15.80) |
| Payment Source | ||||
| Private Insurance | 4.9 | 5.7 | 7.1 | 2.63 (1.31 – 5.25) |
| Public Insurance | 8.6 | 14.7 | 18.4 | 3.44 (1.79 – 6.60) |
| Self-Pay, Otherc | 7.0 | 9.9 | 9.4 | 2.82 (1.56 – 5.08) |
| Clinical Characteristics | ||||
| Physician Patient Relationship | ||||
| New Patient | 6.1* | 5.6* | 12.3* | 4.14 (0.88 – 19.38) |
| Established Patient | 6.1 | 8.6 | 11.1 | 2.71 (1.77 – 4.17) |
| Physician Specialty | ||||
| Other | 2.3 * | 4.6 | 4.7 | 2.85 (1.29 – 6.32) |
| Psychiatry | 10.5 | 13.1 | 20.1 | 2.91 (1.87 – 4.55) |
| Major Depressive Disorder | ||||
| No | 3.8 | 5.7 | 7.1 | 3.16 (1.75 – 5.71) |
| Yes | 11.0 | 14.2 | 20.0 | 2.67 (1.62 – 4.39) |
| Anxiety Disorder | ||||
| No | 5.4 | 7.5 | 10.3 | 2.97 (1.85 – 4.78) |
| Yes | 11.3 | 15.3 | 17.7 | 2.23 (1.19 – 4.20) |
| Other Mental Health Condition | ||||
| No | 4.1 | 5.8 | 7.6 | 3.19 (1.76 – 5.77) |
| Yes | 9.7 | 12.6 | 14.2 | 2.41 (1.48 – 3.91) |
| Diabetes, Hyperlipidemia or CVD | ||||
| No | 7.1 | 8.7 | 11.2 | 2.57 (1.71 – 3.88) |
| Yes | 1.7 * | 7.3 * | 7.2 * | 9.65 (1.76 – 53.07) |
| Psychotherapy Provided | ||||
| No | 5.1 | 7.4 | 8.8 | 3.07 (1.78 – 5.17) |
| Yes | 9.6 | 11.0 | 15.5 | 2.52 (1.49 – 4.26) |
Data from NAMCS. Visits with diagnoses for schizophrenia, bipolar disorder, pervasive development disorder, psychotic depression, or dementia were excluded
Based on pooled NAMCS data from 1999–2010.
Estimates from the logistic regression models in which the dependent variable is AP prescription. We report the coefficients of the transformed survey year variable, converted to odds ratios. The models were calculated separately for each subpopulation and control for all remaining covariates.
Includes self pay, worker’s comp., no charge/charity and others. Rates are based on weighted calculations therefore reflect national estimates. SGA, denotes second generation antipsychotic medication.
Cells size is less than 30. SGA denotes second generation antipsychotic medication. CVD denotes cardiovascular disease