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Effect of Roflumilast in HFD-induced obese mice. (A) Histological sections of visceral adipose tissue; (B) quantification of adipocyte size; (C) Visceral adipose tissue weight; (D) Bodyweight (*, **, ***, P < 0.05, 0.01, 0.005 vs. vehicle group; #, ##, P < 0.05, 0.01 vs. HFD group, n = 8).
