Table 1.
MYD88 splice isoforms.
| MyD88 isoforms | mRNA | Protein | Expression construct MW (incl. Strep-HA tag; kDa)* | ||||
|---|---|---|---|---|---|---|---|
| Reference ID | CDS (bp) | Reference ID | Length (aa) | MW (kDa) | |||
| Isoform 1 | ENST00000421516.3 NM_001172567.2 |
915 | ENSP00000391753 NP_001166038.2 |
304 | 34.1 | 40.5 | |
| Isoform 2 | ENST00000396334.8 NM_002468.5 |
891 | ENSP00000379625 NP_002459.3 |
296 | 33.0 | 37.4 | |
| Isoform 3 (MyD88s) |
ENST00000417037.7 NM_001172568.2 |
795 | ENSP00000401399 NP_001166039.2 |
264 | 29.6 | 34.7 | |
| Isoform 4 | ENST00000651800.1 NM_001172569.3 |
615 | ENSP00000499012 NP_001166040.2 Uniprot: Q99836-3 |
204 | 22.1 | 27.2 | |
| Isoform 5 | ENST00000650112.1 NM_001172566.2 |
480 | ENSP00000497991 Uniprot: Q99836-4 |
159 | 17.2 | 22.8 | |
| Isoform 6 | ENST00000652213 NM_001365876.1 |
738 | ENSP00000498576 NP_001352805.1 |
245 | 27.1 | 34.9§ | |
| Isoform 7 | NM_001365877.1 | 642 | NP_001352806.1 | 213 | 23.5* | 29.9§ | |
| Isoform 8 | ENST00000652590.1 | 723 | n/a (new) | 240 | 26.4* | 32.8§ | |
Reference IDs from Ensembl and NCBI. ENST: cDNA sequence, ENSP: protein sequence, NM: curated NCBI mRNA; Protein-coding transcript, NP, NCBI protein coding sequence; Strep-HA, Strep III - Hemagglutinin tag; n/a, not available. *Values were calculated using ExPASy. § Generated constructs use Met1 as start codon.