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. 2021 Jun 7;12:622471. doi: 10.3389/fimmu.2021.622471

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Copyright © 2021 Telegin, Chernov, Kazakov, Romanova, Sharapova, Yashin, Gabibov and Sashchenko

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fragments of the synovial membrane (left column) and the articular surfaces of hyaline cartilage (right column) of the left ankle joint of a mouse at day 10 in the control (A) and in the model of CFA-induced arthritis after injections of normal saline (B), peptide 17.1A (C), Norocarp (D), peptide 17.1 (E). The severity of synovitis and synovial hyperplasia (white arrows), as well as articular cartilage damage (black arrows) were assessed semi-quantitatively. H&E staining. Magnification 100×.