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. 2021 Jun 21;40:200. doi: 10.1186/s13046-021-01994-8

Table 2.

Correlation between IMP3, MEKK1, MEK1, p-ERK expression and clinicopathologic features in 282 cases of CRC tissues.

Parameters n IMP3 MEKK1 MEK1 p-ERK
- + P value - + P value - + P value - + P value
Age(years)
 <57 133 60 73 0.411 35 98 0.470 34 99 0.785 58 75 0.908
 ≥57 149 60 89 45 104 36 113 66 83
Gender
 Male 165 66 99 0.303 50 115 0.392 37 128 0.268 71 94 0.705
 Female 117 54 63 30 87 33 84 53 64
AJCC stage
 I+II 102 54 48 0.008* 37 65 0.027* 28 74 0.442 54 48 0.022*
 III+IV 180 66 114 43 137 42 138 70 110
T stage
 T1+T2 47 27 20 0.024* 17 30 0.194 12 35 0.902 25 22 0.163
 T3+T4 235 93 142 63 172 58 177 99 136
N stage
 N0 117 60 57 0.013* 41 76 0.036* 33 84 0.268 58 59 0.111
 N1+N2 165 60 105 39 126 37 128 66 99
M stage
 Yes 46 14 32 0.069 12 34 0.707 10 36 0.597 17 29 0.295
 No 236 106 130 68 168 60 176 107 129
Differentiation
 Poor 69 33 36 0.308 21 48 0.661 17 52 0.967 31 38 0.854
 Well and moderate 213 87 126 59 154 53 160 93 120