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. 2021 Jun 21;7:10. doi: 10.1186/s40851-021-00175-x

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Major transporters responsible for Na⁺ and Cl⁻ absorption (blue rectangles) and water absorption (red rectangle) in the intestinal epithelia of SW eels. K⁺ extrusion at the mucosal side and Cl⁻ extrusion at the serosal side (black rectangles) produce the serosa-negative potential difference typical of the marine teleost intestine. For the molecular identities of NHE and AE, see Fig. 6. The local increase in osmolality in the lateral interspace (LIS) produced by NKA stimulates water flux into the space through the AQP and tight junction (TJ). The flows of ions and water within the cell are shown by arrows. The text size for the transporters indicates the relative abundance and upregulation of the transporters in SW. For details, see 4.1.1. For abbreviation definitions, see the list