TABLE 5.
HABLE Characteristics – Blood Biomarker Biomarkers
| Total Cohort N = 1705 | Mexican American N = 890 | Non‐Hispanic White N = 813 | |
|---|---|---|---|
| Plasma AT(N) Markers | |||
| Plasma A | |||
| Aβ40 | 252.55 (67.69) | 239.25 (67.31) | 267.30 (65.06)*** |
| Aβ42 | 12.06 (3.31) | 11.86 (3.41) | 12.26 (3.18) |
| Plasma T (total tau) | 2.47 (0.96) | 2.57 (0.98) | 2.35 (0.92)*** |
| Plasma N (NfL) | 18.97 (11.36) | 17.31 (11.47) | 20.81 (10.98) |
| Metabolic Endophenotype | |||
| PPY | 634.01 (377.71) | 606.95 (386.84) | 660.91 (366.43) |
| PYY | 44.26 (29.77) | 41.81 (27.90) | 46.63 (31.34) |
| GLP1 | 1.32 (1.64) | 1.44 (1.83) | 1.20 (1.14) |
| Insulin | 295.65 (268.99) | 344.47 (301.70) | 247.07 (221.93)*** |
| Glucagon | 64.30 (44.83) | 66.93 (46.08) | 61.43 (43.00)*** |
| FABP3 | 5032.94 (2267.02) | 4619.31 (2259.08) | 5487.06 (2187.72) |
| Inflammatory Endophenotype | |||
| IL6 | 1.32 (2.20) | 1.42 (2.27) | 1.21 (2.12) |
| CRP | 42875365.58 (67985315.03) | 44341610.06 (69216737.06) | 41288343.28 (66691123.43) |
| TNFα | 3.16 (1.03) | 3.18 (1.04) | 3.14 (1.00) |
NOTE: All blood‐based biomarkers were capped at 4 SD above the mean.
***
p < 0.001 significance after controlling for covariates.