Table 3.
Mixed effects model of longitudinal changes
| Group 1 (n = 84) | Group 2 (n = 43) | |||
|---|---|---|---|---|
| Variables | Mean 5 year change (95% CI) | p-value | Mean 5 year change (95% CI) | p-value |
| RV LGE score | − 0.88 (− 1.12, − 0.64) | < 0.001 | − 0.54 (− 1.07, − 0.01) | 0.047 |
| % RV LGE extent | − 2.34 (− 2.91, − 1.76) | < 0.001 | − 1.92 (− 3.18, − 0.67) | 0.004 |
| RVEDVI (ml/m2) | 1.63 (− 2.37, 5.63) | 0.421 | − 42.2 (− 60.0, − 24.4) | < 0.001 |
| RVESVI (ml/m2) | 4.07 (1.15, 6.98) | 0.007 | − 19.1 (− 28.9, − 9.27) | < 0.001 |
| RVEF (%) | − 2.81 (− 3.92, − 1.71) | < 0.001 | − 3.11 (− 5.97, − 0.26) | 0.033 |
| PR fraction (%) | 1.36 (− 0.04, 2.76) | 0.057 | − 24.1 (− 33.4, − 14.9) | < 0.001 |
| RV Mass/BSA, g/m2 | − 0.28 (− 1.03, 0.48) | 0.470 | − 3.46 (− 5.53, − 1.39) | 0.002 |
| RV Mass:Volume, g/ml | − 0.004 (− 0.01, 0.03) | 0.243 | 0.01 (− 0.006, 0.03) | 0.212 |
p-values < 0.05 denote that the slope of longitudinal change differs significantly from zero. Group 1—patients with no interventions between serial CMRs; Group 2—patients with transcatheter or surgical interventions between CMRs. BSA body surface area, CMR cardiovascular magnetic resonance, EDVI end-diastolic volume index, ESVI end-systolic volume index, EF ejection fraction, PR pulmonary regurgitation, LGE late gadolinium enhancement, RV right ventricle