Table 3.
Risk of having a minor allele in rs73375428 (G) or APOE ɛ4 on Aβ positivity
| rs73375428 | APOE ɛ4 | |||
|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | |
| Total (n = 1190) | 0.519 (0.404–0.666) | < 0.001 | 5.330 (4.188–6.788) | < 0.001 |
| CU (n = 383) | 0.486 (0.244–0.964) | 0.030 | 3.885 (2.307–6.54) | < 0.001 |
| aMCI (n = 330) | 0.463 (0.286–0.749) | 0.001 | 6.655 (4.101–10.8) | < 0.001 |
| ADD (n = 477) | 0.685 (0.370–1.270) | 0.230 | 4.272 (2.428–7.516) | < 0.001 |
Logistic regression analysis was adjusted for age and sex
Abbreviations: ADD Alzheimer’s disease dementia, aMCI amnestic mild cognitive impairment, CU cognitive unimpaired, OR odds ratio