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. 2021 Jun 21;10:20. doi: 10.1186/s40035-021-00242-5

Fig. 4.

Fig. 4

Propagation of α-syn pathology from spinal cord to brain in each group. a–d Distribution of pSer129 α-syn in the cervical spinal cord and propagation of α-syn pathology from skeletal muscle to the upper brainstem including medulla oblongata and pons of the brain. Scale bar, 10 μm. e–h Statistical analysis in the above brain regions (one-way ANOVA with Tukey’s multiple comparison tests, n = 3 *P < 0.05, **P < 0.01). Mean ± SD