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. Author manuscript; available in PMC: 2021 Jun 21.
Published in final edited form as: J Cell Biochem. 2009 Oct 1;108(2):508–518. doi: 10.1002/jcb.22280

Fig. 3.

Fig. 3.

SSRP1 depleted cells are inflicted with more DNA damage in response to hydroxyurea. Visualization of Rad51 (A), H2AX (C) foci in inducible SSRP1 siRNA expressing H1299 cells by immunofluorescence staining. The magnified cells are circled (white dotted lines) on the respective overlay image. The siRNA expressing cells were induced with Doxycycline for 3 days prior to a 24 h treatment with HU (200 μM). The mean percentage of SSRP1 depleted cells containing Rad51 (B) and H2AX foci (D) in response to HU treatment was calculated.