Table 1.
Clinical Characteristics of GCT survivors.
Subject number | Sex | Age at diagnosis (years) | Length of time since treatment (years) | Types of germinoma | Tumor Loci | Size of GCT (largest length in cm) | Presence of hydrocephalus at presentation | Treatment | Total RT dosage (Gy) | RT field CSI + tumor boost dose (Gy) |
---|---|---|---|---|---|---|---|---|---|---|
1 | M | 11.7 | 9.3 | GCT | Basal ganglia | 0.7 | No | C + RT | 30.6 | CSI (21.6) + TB (9) |
2 | M | 15.1 | 10.9 | NGGCT | Basal ganglia | 3.0 | No | C + RT | 50.0 | IFRT |
3 | M | 8.8 | 1.2 | NGGCT | Pineal | 1.1 | Yes | C + RT | 46.8 | CSI (30.6) + TB (16.2) |
4 | M | 17.9 | 3.1 | GCT | Others - Bifocal | 2.3 | No | C + RT | 30.0 | WVRT + TB |
5 | M | 9.7 | 8.3 | GCT | Basal ganglia | 3.0 | No | C + RT | 50.4 | WVRT + TB |
6 | F | 10.7 | 5.3 | NGGCT | Sellar/suprasellar | 3.9 | No | S, C + RT | 54.0 | CSI (36) + TB (18) |
7 | M | 17.2 | 6.8 | GCT | Pineal | 0.9 | Yes | C + RT | 30.0 | CSI (22.5) + TB (7.5) |
8 | F | 17.5 | 6.5 | GCT | Sellar/suprasellar | 3.1 | No | S, C + RT | 36.0 | WVRT + TB |
9 | F | 15.8 | 3.2 | NGGCT | Sellar/suprasellar | 2.4 | No | S, C + RT | 54.0 | CSI (36) + TB (18) |
10 | M | 17.3 | 9.7 | GCT | Sellar/suprasellar | 1.4 | No | C + RT | 48.0 | WBRT |
11 | M | 13.8 | 12.2 | GCT | Basal ganglia | 6.0 | No | C + RT | 52.2 | WBRT |
12 | F | 7.7 | 7.3 | NGGCT | Others - Bifocal | 4.2 | No | C + RT | 45.0 | CSI (24) + TB (21) |
13 | F | 9.8 | 6.2 | GCT | Sellar/suprasellar | 1.0 | No | C + RT | 45.0 | WVRT + TB |
14 | M | 15.2 | 9.8 | GCT | Pineal | 2.7 | Yes | C + RT | 45.5 | CSI (25.5) + TB (20) |
15 | M | 10.9 | 6.1 | GCT | Pineal | 2.0 | Yes | S, C + RT | 45.0 | WBRT |
16 | M | 16.7 | 1.3 | GCT | Sellar/suprasellar | 4.1 | No | C + RT | 36.0 | WBRT |
17 | M | 17.5 | 2.5 | NGGCT | Others - Brainstem | 3.3 | No | S, C + RT | 54.0 | CSI (36) + TB (18) |
18 | M | 10.8 | 8.2 | NGGCT | Sellar/suprasellar | 1.3 | No | S, C + RT | 30.0 | WVRT + TB |
19 | M | 17.3 | 9.7 | GCT | Others - Bifocal | 4.2 | No | C + RT | 30.6 | CSI (23.4) + TB (7.2) |
20 | M | 10.9 | 1.8 | NGGCT | Basal ganglia | 3.5 | No | C + RT | 54.0 | WVRT + IFRT |
C, chemotherapy; S, surgery; RT, radiotherapy; GCT, germ cell tumors; CSI, cranial spinal irradiation; IFRT, involved field radiotherapy; WBRT, whole brain radiotherapy; WVRT, whole ventricular radiotherapy; TB, tumor boost.
GCT, Germ Cell Tumor; NGGCT, Nongerminomatous Germ Cell Tumor.