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. 2021 Jun 7;11:655302. doi: 10.3389/fonc.2021.655302

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Copyright © 2021 Liu, Wang, Geng, Wang, Han, You, Sun, Zhang, Lu and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CD155 affects the biological behavior of cervical cancer cells. CaSki and HeLa cells were transfected with NC-CD155, si-CD155, PCMV-NC, and PCMV-CD155. (A) The viability of Hela and CaSki cells was measured by using the CCK8 assay. (B) Apoptosis was detected by flow cytometry after staining with Annexin V-APC and 7AAD. (C) Cell cycle analysis by flow cytometry. (D) Transwell assays were used to assess the invasion and migration capacity of CaSki and HeLa cells in which CD155 was overexpressed or knocked down. The data are the mean ± SEM of at least three independent experiments. *P < 0.05.