Skip to main content
. 2021 Jun 7;11:655302. doi: 10.3389/fonc.2021.655302

Figure 6.

Figure 6

CD155 overexpression promotes cervical cancer growth in vivo. (A) Images of xenograft tumors derived from cells transfected with PCMV-CD155 or PCMV-NC. (B) The volumes of xenograft tumors derived from cells transfected with PCMV-CD155 or PCMV-NC. (C) The weight of xenograft the formed tumors derived from cells transfected with PCMV-CD155 or PCMV-NC. (D) Western blotting was used to detect protein expression in tumor forming tissues in vivo. The LC3BII/LC3BI ratio and protein expression of Beclin-1 were significantly decreased in the PCMV-CD155 group, while the protein expression of p-AKT, p-mTOR, P-IKKα/β and Ki67 was significantly increased. All data represent three independent experiments. The data were the mean ± SEM of at least three independent experiments. (E) Images of HE staining of xenograft tumors (200x). The expression of p-AKT, Ki67, and p-NF-κBp65 in xenograft tumors was detected by IHC (200x). *P < 0.05, **P < 0.01.