Figure 2.

Visualization of the multi-compartmental metabolic reaction network of metabolites identified to differ between monkeys that recovered gradually from ID (pID) when compared to always iron sufficient (IS) or ones supplemented with iron when determined to be ID (pID+Fe). The network includes reactions that can be performed by the monkey host (solid lines) or by bacteria present in the gut (dashed lines). The color of the line indicates reactions that require or involve iron. Grey boxes indicate urinary or plasma metabolites that differed between pID and IS or pID+Fe monkeys. White boxes indicate intermediate metabolites; boxes with an orange border indicate metabolites involved in reactions requiring or involving iron.