Table 1.
RNA-binding protein consensus motifs and target transcript characteristics
RNA-bindingprotein |
Binding motif(s) |
Predominant regions of binding within target transcripts |
FMRP | WGGA, GACR and TAY; G-quadruplex | Coding regions and 3’ UTR in a subset of transcripts |
RBFOX1 | (U)GCAUG | Introns and 3’ UTR |
TDP-43 | UG repeats; G-quadruplex |
Introns; 3’ UTR and 5’UTR |
FUS | GGUG; G-quadruplex |
Introns; 3’UTR |