Table 4:
Associations between maternal inflammatory biomarkers during pregnancy and infant birth and adiposity outcomes.
| Birth weight (g) (n=515) | Gestational age (days) (n=515) | Adiposity at birth (%) (n=497) | Adiposity at postnatal (~5 months) follow-up (%) (n=334) | |
|---|---|---|---|---|
| β (95% CI) per log-unita | β (95% CI) per log-unita | β (95% CI) per log-unita | β (95% CI) per log-unitb | |
| CRP (mg/L) | 12.48 (−31.31, 56.27) | 1.30 (0.40, 2.21) | 0.06 (−0.34, 0.45) | 0.43 (−0.26, 1.12) |
| IL-6 (pg/mL) | 10.51 (−66.94, 87.95) | 0.24 (−1.37, 1.86) | 0.23 (−0.47, 0.93) | −0.04 (−1.30, 1.21) |
| TNFα (pg/mL) | 23.30 (−22.72, 69.31) | 0.29 (−0.67, 1.25) | −0.11 (−0.53, 0.31) | −0.14 (−0.91, 0.63) |
Abbreviations: 95% CI, 95% Confidence Interval; CRP, C-reactive protein; IL-6 interleukin-6; TNFα, tumor necrosis factor-α
All maternal inflammatory biomarker outcomes were natural log transformed.
a
Adjusted for race, maternal age, median income in the Census tract, pre-pregnancy BMI, education, smoking status, gestational age at sample collection, infant sex, and parity.
b
Additionally adjusted for infant age at the time of adiposity measurement.