Figure 7.

Targeting capability of cRGD-Exo-PTX in vitro and in vivo. (a) Schematic diagram of the synthesis of cRGD-Exo-PTX. (b) Cell viability of PBS (CTL group), PTX, Exo-PTX, and cRGD-Exo-PTX groups during targeted therapy was determined using the CCK-8 assay. U87 and U251 are two human GBM cell lines. (c) Schematic diagram of subcutaneous U87 GBM in different groups and tumor volumes measured at specified time points during in vitro targeted therapy. Reproduced with permission from reference (Zhu et al., 2019).