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. 2021 Mar 2;49(11):e63. doi: 10.1093/nar/gkab135

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — NMR fingerprints of the U1 snRNP tails. (A) Overlay of the 2D ¹H-¹⁵N TROSY HSQC spectra of Sm B-D₃ (black) and Sm B-D₃ embedded in U1 snRNP (blue). (B) Overlay of the 2D ¹H-¹⁵N TROSY HSQC spectra of Sm D₁-D₂ (black) and Sm D₁-D₂ embedded in U1 snRNP (yellow). (C) Overlay of the 2D ¹H-¹⁵N TROSY HSQC spectra of U1-C in complex with unlabeled Sm B-D₃ (black) and U1-C embedded in U1 snRNP (red). (D) Overlay of the 2D ¹H-¹⁵N TROSY HSQC spectra of U1-A (black) and U1-A embedded in U1 snRNP (green). On each spectrum, a representation of the 3D structure of U1 snRNP is shown (17).