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. 2021 May 28;49(11):6511–6528. doi: 10.1093/nar/gkab432

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© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — The structural and regulatory zinc binding sites of XcZur. (A) Close-up view of the structural zinc binding site (site 1) of apo XcZur. The zinc atom is represented by a red sphere and the corresponding coordination ligands are shown in colored sticks. (B) Close-up view of the structural zinc binding site of holo XcZur. (C) Close-up view of the regulatory zinc binding site (site 2) of apo XcZur. Key residues in this site are shown in colored sticks. The characteristic β hairpin in DBD are shown in red. (D) Close-up view of the regulatory zinc binding site of holo XcZur. (E) Binding activity of wild type and site 1-related mutants of XcZur with P₀₂₆₇. (F) Binding activity of wild type and site 2-related mutants of XcZur with P₀₂₆₇.