Fig. 2.
P62 gene silencing reverses phenotype transition and proliferation in CD38−/− or baf treated CAMs. (A) Representative western blot gel documents, (B and C) summarized densitometric data and (D) representative confocal microscopic fluorescent images showing relative abundance of vimentin to calponin or α-SMA in CD38+/+ or CD38−/− CAMs under ctrl or baf treatment transfected by scrambled sRNA (sc) or p62 siRNA (si). (E and F) Summarized data showing the relative proliferation rate of CD38+/+ or CD38−/− CAMs detected by MTS (E) or Trypan blue (F) assay. Data are shown as means±SEM, n=5, *P<0.05 vs. CD38+/+ ctrl with sc transfection.