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(A) Qualitative cell cycle progress and (C) quantitative cell cycle analysis of C6 cell lines treated with different samples. (B, D) Qualitative and quantitative apoptotic progression of C6 cell lines treated with control (TMZ/CUR), TMZ-NLCs, CUR-NLCs and TMZ/CUR-NLCs (2:1). (E) Illustration shows the proposed mechanism behind the synergistic anticancer effect of TMZ/CUR-NLCs (2:1) against glioma cells. The statistical significance is expressed as **p < .01, *p < .05.
