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. 2020 Jul 5;27(1):1034–1043. doi: 10.1080/10717544.2020.1787555

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Better sustained analgesic effects of flurbiprofen thermogel. The sequential Knee-Bend (A) and CatWalk (B) tests performed on the rats in each experimental group at the time points of 0, 2, 4, 8, 12, 24, 36, 48, and 72 hour after the first-time drug treatments. Significant differences of the final scores are established between flurbiprofen gel group and the other experimental groups (p < .05). *p < .01 between the flurbiprofen gel group and the untreated group; **p < .05 between the flurbiprofen gel group and the HA group; ***p < .05 between the flurbiprofen gel group and the flurbiprofen group.