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. 2021 Jun 4;49(11):6213–6237. doi: 10.1093/nar/gkab437

Table 1.

Statistical analysis of the differential levels of DNA methylation within the CD44 gene among the MCF10A-derived cells analysed in Figure 9D. Indicated Groups of loci for comparison were tested by pairwise Student's t test (two-tailed) evaluating differences from locus to locus. The P-values of these tests for each cell line compared to MCF10A parental cells or CA1A versus DCIS are reported in the Table. The non-significant P-values are in italic.

Comparison versus MCF10A versus DCIS
MCF10A(Ras) DCIS CA1A CA1A
Differences on:
all loci tested 1.4E-07 2.8E-07 5.7E-04 4.3E-05
constant exons 0.001 0.107 0.127 0.298
variant region inluding introns (i10, i11, i15) 1.1E-04 5.0E-04 0.006 0.004
variant exons only 0.003 0.005 0.029 0.012
introns only 0.035 0.050 0.043 0.068