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. 2021 Jun 14;49(11):6114–6127. doi: 10.1093/nar/gkab499

Figure 7.

Figure 7.

Discrimination factors (DF = kmatch/kmismatch) of PNA–DNA heteroduplexes towards RNA inputs having different mismatches, where kmatch and kmismatch are the calculated rate constants for a fully matched and mismatched RNA input, respectively. Error bars represent standard deviation from three independent experiments. Hetero and Homo refer to the heterochiral and homochiral reactions pathways, respectively. See Figure 3A for mismatch identity and position.