Table 10.
Time (hr) | IOP (mmHg) lowering effects of G2 and marketed formulation |
|||
---|---|---|---|---|
Group II (G2) |
Group III (marketed Pilopine HS gel) |
|||
R | L | R | L | |
0 | 40.47 ± 0.42 | 40.47 ± 0.04 | 40.07 ± 0.19 | 40.07 ± 0.02 |
2 | 40.47 ± 0.42 | 35.12 ± 0.17 | 40.07 ± 0.19 | 30.95 ± 1.68 |
4 | 40.47 ± 0.42 | 27.89 ± 0.28 | 40.07 ± 0.19 | 27.37 ± 2.32 |
6 | 40.47 ± 0.42 | 23.85 ± 0.31 | 40.07 ± 0.19 | 21.69 ± 0.45 |
7 | 40.47 ± 0.42 | 21.20 ± 0.53 | 40.07 ± 0.19 | 17.42 ± 1.12 |
8 | 40.47 ± 0.42 | 19.28 ± 0.06 | 40.07 ± 0.19 | 20.95 ± 3.21 |
9 | 40.47 ± 0.42 | 17.98 ± 1.35 | 40.07 ± 0.19 | 21.69 ± 0.57 |
10 | 40.47 ± 0.42 | 19.54 ± 2.31 | 40.07 ± 0.19 | 24.23 ± 1.12 |
11 | 40.47 ± 0.42 | 20.94 ± 0.96 | 40.07 ± 0.19 | 28.96 ± 4.96 |
24 | 40.47 ± 0.42 | 21.93 ± 1.24 | 40.07 ± 0.19 | 40.01 ± 0.43 |