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. Author manuscript; available in PMC: 2021 Jul 9.
Published in final edited form as: J Med Chem. 2020 Jun 9;63(13):7243–7251. doi: 10.1021/acs.jmedchem.0c00475

Figure 1.

Figure 1.

Analysis of LQZ-7 binding to survivin and synthesis of LQZ-7 analogues. (A) Molecular dynamic simulation analysis of LQZ-7 bound to the dimeric interface of survivin. (B) Critical interactions between LQZ-7 and survivin. (C) Scheme of LQZ-7 analogue (quinoxaline derivatives) synthesis.