Table 2. Raw means and standard deviations of cardiorespiratory parameters measured preceding a cough trial.
(A.) Respiratory parameters measured include respiratory rate (breaths/min), end-tidal CO2 (ETCO2, mmHg), TI, TE, and TTOT phases of breathing (ms), and diaphragm EMG amplitude (% maximum). (B.) Cardiovascular measures were also recorded including systolic, diastolic, mean arterial pressure (MAP), and pulse pressure (PP) (mmHg) as well as heart rate (beats/min) preceding each cough trial.
| A. Eupnea | Condition | Animal # | Resp Rate (breath/min) | ETCO2 (mmHg) | TI (ms) | TE (ms) | TTOT (ms) | Diaphram EMG (% max) |
| Control | 1 | 21 ± 2 | 31 ± 1 | 1416 ± 214 | 1456 ± 170 | 2873 ± 294 | 46 ± 5 | |
| Control | 2 | 36 ± 1 | 22 ± 1 | 462 ± 49 | 1203 ± 53 | 1665 ± 88 | 51 ± 9 | |
| Control | 3 | 26 ± 1 | 35 ± 1 | 1167 ± 84 | 1180 ± 29 | 2346 ± 98 | 93 ± 5 | |
| Control | 4 | 21 ± 2 | 28 ± 1 | 1895 ± 481 | 978 ± 74 | 2873 ± 506 | 76 ± 4 | |
| Control | 5 | 26 ± 5 | 29 ± 2 | 956 ± 267 | 1416 ± 227 | 2372 ± 479 | 32 ± 6 | |
| Control | 6 | 26 ± 0 | 29 ± 1 | 762 ± 43 | 1531 ± 135 | 2293 ± 172 | 83 ± 8 | |
| Control | 7 | 14 ± 1 | 34 ± 0 | 1789 ± 109 | 2504 ± 351 | 4293 ± 423 | 91 ± 6 | |
| Control | 8 | 23 ± 0 | 31 ± 1 | 1601 ± 338 | 1005 ± 43 | 2607 ± 369 | 92 ± 2 | |
| Control | 9 | 31 ± 1 | 28 ± 0 | 540 ± 27 | 1423 ± 64 | 1964 ± 66 | 84 ± 5 | |
| >1-hr post | 1 | 12 ± 1 | 26 ± 0 | 1797 ± 85 | 3389 ± 267 | 5186 ± 333 | 96 ± 3 | |
| >1-hr post | 2 | 19 ± 1 | 34 ± 0 | 948 ± 68 | 2250 ± 222 | 3198 ± 242 | 91 ± 7 | |
| >1-hr post | 3 | 23 ± 0 | 29 ± 1 | 990 ± 180 | 1582 ± 198 | 2573 ± 55 | 82 ± 2 | |
| >1-hr post | 4 | 33 ± 2 | 24 ± 2 | 965 ± 133 | 879 ± 63 | 1845 ± 172 | 80 ± 8 | |
| >1-hr post | 5 | 43 ± 1 | 16 ± 0 | 773 ± 37 | 633 ± 26 | 1406 ± 53 | 29 ± 2 | |
| >1-hr post | 6 | 21 ± 1 | 27 ± 1 | 966 ± 97 | 1886 ± 147 | 2851 ± 215 | 88 ± 3 | |
| >1-hr post | 7 | 14 ± 2 | 33 ± 1 | 1149 ± 200 | 3310 ± 752 | 4458 ± 585 | 55 ± 9 | |
| >1-hr post | 8 | 20 ± 2 | 23 ± 0 | 1362 ± 156 | 1669 ± 157 | 3031 ± 293 | 87 ± 5 | |
| >1-hr post | 9 | 26 ± 0 | 26 ± 0 | 802 ± 87 | 1496 ± 53 | 2299 ± 109 | 97 ± 2 | |
| 10-min post | 5 | 25 ± 2 | 23 ± 2 | 1204 ± 721 | 1201 ± 235 | 2405 ± 505 | 34 ± 27 | |
| 10-min post | 6 | 16 ± 1 | 28 ± 1 | 907 ± 67 | 2752 ± 170 | 3659 ± 185 | 90 ± 4 | |
| 10-min post | 7 | 14 ± 0 | 34 ± 0 | 976 ± 83 | 3232 ± 199 | 4208 ± 226 | 54 ± 3 | |
| 10-min post | 8 | 14 ± 0 | 31 ± 1 | 1810 ± 59 | 2459 ± 168 | 4269 ± 182 | 96 ± 5 | |
| 10-min post | 9 | 23 ± 1 | 26 ± 1 | 778 ± 45 | 1785 ± 90 | 2563 ± 115 | 91 ± 3 | |
| Average | Control | 25 ± 6 | 30 ± 4 | 1177 ± 532 | 1411 ± 456 | 2587 ± 750 | 72 ± 23 | |
| >1-hr post | 23 ± 10 | 26 ± 5 | 1084 ± 320 | 1899 ± 955 | 2983 ± 1200 | 78 ± 22 | ||
| 10-min post | 19 ± 5* | 29 ± 4 | 1135 ± 408 | 2286 ± 802 | 3421 ± 889 | 73 ± 27 |
Tukey’s HSD test used to compare timepoints.
* = p < 0.05,
** = p < 0.01,
*** p < 0.001.
n = 7.