Skip to main content
. 2021 Jun 21;16(6):e0253060. doi: 10.1371/journal.pone.0253060

Table 2. Raw means and standard deviations of cardiorespiratory parameters measured preceding a cough trial.

(A.) Respiratory parameters measured include respiratory rate (breaths/min), end-tidal CO2 (ETCO2, mmHg), TI, TE, and TTOT phases of breathing (ms), and diaphragm EMG amplitude (% maximum). (B.) Cardiovascular measures were also recorded including systolic, diastolic, mean arterial pressure (MAP), and pulse pressure (PP) (mmHg) as well as heart rate (beats/min) preceding each cough trial.

A. Eupnea Condition Animal # Resp Rate (breath/min) ETCO2 (mmHg) TI (ms) TE (ms) TTOT (ms) Diaphram EMG (% max)
Control 1 21 ± 2 31 ± 1 1416 ± 214 1456 ± 170 2873 ± 294 46 ± 5
Control 2 36 ± 1 22 ± 1 462 ± 49 1203 ± 53 1665 ± 88 51 ± 9
Control 3 26 ± 1 35 ± 1 1167 ± 84 1180 ± 29 2346 ± 98 93 ± 5
Control 4 21 ± 2 28 ± 1 1895 ± 481 978 ± 74 2873 ± 506 76 ± 4
Control 5 26 ± 5 29 ± 2 956 ± 267 1416 ± 227 2372 ± 479 32 ± 6
Control 6 26 ± 0 29 ± 1 762 ± 43 1531 ± 135 2293 ± 172 83 ± 8
Control 7 14 ± 1 34 ± 0 1789 ± 109 2504 ± 351 4293 ± 423 91 ± 6
Control 8 23 ± 0 31 ± 1 1601 ± 338 1005 ± 43 2607 ± 369 92 ± 2
Control 9 31 ± 1 28 ± 0 540 ± 27 1423 ± 64 1964 ± 66 84 ± 5
>1-hr post 1 12 ± 1 26 ± 0 1797 ± 85 3389 ± 267 5186 ± 333 96 ± 3
>1-hr post 2 19 ± 1 34 ± 0 948 ± 68 2250 ± 222 3198 ± 242 91 ± 7
>1-hr post 3 23 ± 0 29 ± 1 990 ± 180 1582 ± 198 2573 ± 55 82 ± 2
>1-hr post 4 33 ± 2 24 ± 2 965 ± 133 879 ± 63 1845 ± 172 80 ± 8
>1-hr post 5 43 ± 1 16 ± 0 773 ± 37 633 ± 26 1406 ± 53 29 ± 2
>1-hr post 6 21 ± 1 27 ± 1 966 ± 97 1886 ± 147 2851 ± 215 88 ± 3
>1-hr post 7 14 ± 2 33 ± 1 1149 ± 200 3310 ± 752 4458 ± 585 55 ± 9
>1-hr post 8 20 ± 2 23 ± 0 1362 ± 156 1669 ± 157 3031 ± 293 87 ± 5
>1-hr post 9 26 ± 0 26 ± 0 802 ± 87 1496 ± 53 2299 ± 109 97 ± 2
10-min post 5 25 ± 2 23 ± 2 1204 ± 721 1201 ± 235 2405 ± 505 34 ± 27
10-min post 6 16 ± 1 28 ± 1 907 ± 67 2752 ± 170 3659 ± 185 90 ± 4
10-min post 7 14 ± 0 34 ± 0 976 ± 83 3232 ± 199 4208 ± 226 54 ± 3
10-min post 8 14 ± 0 31 ± 1 1810 ± 59 2459 ± 168 4269 ± 182 96 ± 5
10-min post 9 23 ± 1 26 ± 1 778 ± 45 1785 ± 90 2563 ± 115 91 ± 3
Average Control 25 ± 6 30 ± 4 1177 ± 532 1411 ± 456 2587 ± 750 72 ± 23
>1-hr post 23 ± 10 26 ± 5 1084 ± 320 1899 ± 955 2983 ± 1200 78 ± 22
10-min post 19 ± 5* 29 ± 4 1135 ± 408 2286 ± 802 3421 ± 889 73 ± 27

Tukey’s HSD test used to compare timepoints.

* = p < 0.05,

** = p < 0.01,

*** p < 0.001.

n = 7.