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. 2021 Jun 17;15:2593–2603. doi: 10.2147/DDDT.S313714

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© 2021 Wu et al.

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Probability of target attainment (PTA) for a MIC of 1 mg/L in patients with normal renal function and for a MIC of 2 mg/L in patients with renal impairment when efficacy is defined as 50 AUC/MIC, and toxicity is defined as an AUC >100 mg∙h/L at steady state for polymyxin B doses administered to patients.