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. 2021 Jun 17;16:4147–4159. doi: 10.2147/IJN.S303829

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© 2021 Hong et al.

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(A) In vivo tumor growth curves of U251-bearing nude mice treated with saline, Cur-solution, Cur-NPs, and Cur-P-NPs. (*P < 0.05; **P < 0.01), (B) Body weight changes of U251-bearing nude mice treated with saline, Cur-solution, Cur-NPs, and Cur-P-NPs.

Abbreviations: Cur-solution, curcumin dissolved in DMSO:H₂O at 1:1000 (v:v); Cur-NPs, Cur-loaded hybridized nanoparticles; Cur-P-NPs, Cur-loaded enzyme-targeted hybrid nano-delivery systems.