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. 2021 Jun 22;22:182. doi: 10.1186/s12931-021-01778-w

Table 2.

Cox proportional hazard analysis of baseline factors associated with mortality

Variable Univariate Cox model Multivariate Cox model
HR (95%CI) P value HR (95%CI) P value
SOFA 2.973 (2.043–4.327)  < 0.0001 3.507 (1.770–6.948)  < 0.0001
FGF21 3.388 (2.266–5.066)  < 0.0001 11.224 (3.237–38.917)  < 0.0001
IL-6 2.437 (1.769–3.358)  < 0.0001 NA 0.639
TNF-a 3.071 (1.926–4.898)  < 0.0001 NA 0.051
IL-10 3.220 (1.977–5.792)  < 0.0001 NA 0.991
PCT 1.787 (1.339–2.385)  < 0.0001 NA 0.602
CRP 1.011 (1.008–1.015)  < 0.0001 2.029 (1.305–3.155) 0.002
LAC 1.944 (1.462–2.584)  < 0.0001 NA 0.062

Here and below: NA not applicable