Table 4.
Quantitative motor assessment of nocturnal movements in PD patients with and without Levodopa
| Training-PD study | (I) No Levodopa n = 17 | (II) Levodopa n = 13 | (III) Levodopa CR n = 4 | p value |
|---|---|---|---|---|
| Duration of total sleep time (h) | 7.7 (6.6–12.7) | 8.1 (7.0–10.1) | 7.7 (7.1–8.0) | 0.50 |
| Total movement (% of night’s rest) | ||||
| Total detected movementa | 1.8 (0.7–5.7) | 1.9 (1.0–2.9) | 1.7 (0.9–2.7) | 0.79 |
| Movement intensity (mg) | ||||
| Mean MI of movement duration small shiftsb | 44.4 (9.8) | 47.6 (8.4) | 42.1 (7.7) | 0.48 |
| Mean MI of movement duration medium shiftsb | 60.9 (10.2) | 65.8 (12.6) | 62.4 (14.2) | 0.58 |
| Mean MI of movement duration large shiftsb | 80.0 (15.6) | 82.8 (20.4) | 82.2 (19.2) | 0.95 |
| Angular velocity (deg/sec) | ||||
| Mean angular velocity small shiftsb | 5.9 (9.5) | 5.5 (0.7) | 6.3 (0.9) | 0.21 |
| Mean angular velocity medium shiftsb | 10.0 (1.6) | 10.2 (2.3) | 10.4 (2.4) | 0.94 |
| Mean angular velocity large shiftsa | 10.8 (2.6) | 12.2 (3.4) | 10.4 (0.5) | 0.56 |
deg/sec degree per second; h hours; n number; MI movement intensity; p level of significance; PD Parkinson’s disease; s seconds; g gram
aValues presented as median (range)
bValues presented as mean (standard deviation), (I) No Levodopa: no intake of Levodopa during day or night; (II) Levodopa: intake of Levodopa; (III) intake of Levodopa plus Levodopa Continuous Release